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Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study

Identifieur interne : 000234 ( Psycho/Analysis ); précédent : 000233; suivant : 000235

Factors Associated with Psychosis among Patients with Severe Acute Respiratory Syndrome: A Case-Control Study

Auteurs : Dominic T. S. Lee [Hong Kong, États-Unis] ; Y. K. Wing [Hong Kong] ; Henry C. M. Leung [Hong Kong] ; Joseph J. Y. Sung [Hong Kong] ; Y. K. Ng [Hong Kong] ; G. C. Yiu [Hong Kong] ; Ronald Y. L. Chen [Hong Kong] ; Helen F. K. Chiu [Hong Kong]

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RBID : ISTEX:E7E41992DB27E1F0355C80C6068BAD97A75B3920

Abstract

We observed that a number of patients with severe acute respiratory syndrome (SARS) developed affective psychosis during the acute phase of their illness. We reviewed all SARS-related psychiatric consultations in Hong Kong and investigated the risk factors for psychosis among patients with SARS in a matched case-control study. Patients with SARS-related psychosis received higher total doses of steroids and had higher rates of family history of psychiatric illness. The findings of the present study suggest that steroid toxicity, personal vulnerability, and, probably, psychosocial stressors jointly contributed to the development of psychosis in patients with SARS.

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DOI: 10.1086/424016


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ISTEX:E7E41992DB27E1F0355C80C6068BAD97A75B3920

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